L'Aquila (Italy) - Hybrid

13th-15th July, 2022

16th International Conference on Practical Applications of Computational Biology & Bioinformatics

L'Aquila (Italy) | 13th-15th July, 2022 | www.pacbb.net

The success of Bioinformatics in recent years has been prompted by research in Molecular Biology and Molecular Medicine in several initiatives. These initiatives gave rise to an exponential increase in the volume and diversification of data, including nucleotide and protein sequences and annotations, high-throughput experimental data, biomedical literature, among many others.

Systems Biology is a related research area that has been replacing the reductionist view that dominated Biology research in the last decades, requiring the coordinated efforts of biological researchers with those related to data analysis, mathematical modeling, computer simulation and optimization.

The accumulation and exploitation of large-scale data bases prompts for new computational technology and for research into these issues. In this context, many widely successful computational models and tools used by biologists in these initiatives, such as clustering and classification methods for gene expression data, are based on Computer Science/ Artificial Intelligence (CS/AI) techniques. In fact, these methods have been helping in tasks related to knowledge discovery, modeling and optimization tasks, aiming at the development of computational models so that the response of biological complex systems to any perturbation can be predicted.

The 16th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB) aims to promote the interaction among the scientific community to discuss applications of CS/AI with an interdisciplinary character, exploring the interactions between sub-areas of CS/AI, Bioinformatics, Chemoinformatics and Systems Biology.

Brand new ideas in these fields are sought, as well as substantial and relevant revisions and actualizations of previously presented work, project summaries and PhD thesis presented or not.

The proceedings of the previous edition are available:



Special Issues

Authors of selected papers from PACBB 2022 will be invited to submit an extended and improved version to special issue in different journals.

To Be Updated

PACBB'21 awards


“Combinatorial Optimization of SuccinateProduction in Escherichia coli” by Vítor Pereira, and Miguel Rocha


“On the reproducibility of miRNA-Seq differential expression analyses in neuropsychiatric diseases” by Daniel Pérez-Rodríguez, Hugo López-Fernández, and Roberto C. Agís-Balboa

2021 Electronics MDPI Best papers

MDPI Electronics

"Comparison of predictive models with balanced classes for the forecast of student dropout in higher education" by Vaneza Flores-Gutierrez, Stella Heras, and Vicente Julián

"Using Machine Learning to Predict the Users Ratings on TripAdvisor Based on their Reviews" by João Carneiro, Jorge Meira, Paulo Novais and Goreti Marreiros

"Wright's Learning Curve or Rather Butterfly and Bandwagon Effects? On Instabilities in Coevolution of Demand and Supply of Technology" by Ben Vermeulen

"Determining Uncertain Spatial Patterns of Concentrations through Shannon?s Information Entropy: Can Neural Networks Explain Cognitive Relatedness and Local Industrial Structures?" by Vittorio Carlei

"Combinatorial Optimization of SuccinateProduction in Escherichia coli" by Vítor Pereira, and Miguel Rocha

2021 Systems MDPI Best Papers


"A Smart Contract Architecture to Enhance the Industrial Symbiosis Process between the Pulp and Paper Companies - a case study" by Ricardo Gonçalves, Inês Ferreira, Radu Godina, Pedro Pinto, and António Pinto

"Students’ attitude towards Technology Enhanced Photovoice to support critical reflection" by Marije ten Brink, Bert Bredeweg, and Ben Schouten